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These final results, together with a previous report displaying that a small-molecule ACKR3 agonist CCX771 displays anxiolytic-like actions in mice,2 support the idea of targeting ACKR3 as a novel strategy to modulate the opioid procedure, which could open new therapeutic avenues for opioid-linked Conditions.Tabernaemontana divaricata Conolidine is

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